Y59F (p.Tyr59Phe) variant of TUBB2B (Tubulin beta-2B chain)
Y59F (p.Tyr59Phe) in TUBB2B (Tubulin beta-2B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
Y59F (p.Tyr59Phe) variant details
- p.Tyr59Phe
- gnomAD 6-3226260-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.379
- REVEL 0.23
- CADD 22.50
- PolyPhen-2 0.15
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available