V66L (p.Val66Leu) variant of TUBB2B (Tubulin beta-2B chain)
V66L (p.Val66Leu) in TUBB2B (Tubulin beta-2B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
V66L (p.Val66Leu) variant details
- p.Val66Leu
- Ensembl rs1757286302
- Missense
- Variant Prioritization Score for Impact Estimate 0.568
- REVEL 0.46
- CADD 22.40
- PolyPhen-2 0.03
- SIFT 0.08
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available