V5M (p.Val5Met) variant of TUBB2B (Tubulin beta-2B chain)
V5M (p.Val5Met) in TUBB2B (Tubulin beta-2B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
V5M (p.Val5Met) variant details
- p.Val5Met
- TOPMed rs1181218477
- Missense
- Variant Prioritization Score for Impact Estimate 0.612
- REVEL 0.53
- CADD 25.60
- PolyPhen-2 0.23
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available