S115L (p.Ser115Leu) variant of TUBB2B (Tubulin beta-2B chain)
S115L (p.Ser115Leu) in TUBB2B (Tubulin beta-2B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
S115L (p.Ser115Leu) variant details
- p.Ser115Leu
- Ensembl rs1356173511
- Missense
- Variant Prioritization Score for Impact Estimate 0.554
- REVEL 0.59
- CADD 24.60
- PolyPhen-2 0.09
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available