L65R (p.Leu65Arg) variant of TUBB2B (Tubulin beta-2B chain)
L65R (p.Leu65Arg) in TUBB2B (Tubulin beta-2B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
L65R (p.Leu65Arg) variant details
- p.Leu65Arg
- ExAC rs779620048
- gnomAD rs779620048
- Missense
- Variant Prioritization Score for Impact Estimate 0.71
- REVEL 0.79
- CADD 25.00
- PolyPhen-2 0.38
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available