F81Y (p.Phe81Tyr) variant of TUBB2B (Tubulin beta-2B chain)
F81Y (p.Phe81Tyr) in TUBB2B (Tubulin beta-2B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
F81Y (p.Phe81Tyr) variant details
- p.Phe81Tyr
- gnomAD 6-3226194-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.469
- REVEL 0.38
- CADD 22.80
- PolyPhen-2 0.01
- SIFT 0.46
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available