D41D (p.Asp41Asp) variant of TUBB2B (Tubulin beta-2B chain)
D41D (p.Asp41Asp) in TUBB2B (Tubulin beta-2B chain) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
D41D (p.Asp41Asp) variant details
- p.Asp41Asp
- rs748385221
- gnomAD 6-3226604-A-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.217
- AlphaMissense 0.24
- MetaLR 0.13
- MetaSVM -1.00
- CADD 11.60
- PolyPhen-2 0.00
- EVE 0.22
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available