D31E (p.Asp31Glu) variant of TUBB2B (Tubulin beta-2B chain)
D31E (p.Asp31Glu) in TUBB2B (Tubulin beta-2B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
D31E (p.Asp31Glu) variant details
- p.Asp31Glu
- TOPMed rs1459863771
- gnomAD rs1459863771
- Missense
- Variant Prioritization Score for Impact Estimate 0.415
- REVEL 0.39
- CADD 22.80
- PolyPhen-2 0.00
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available