Y8S (p.Tyr8Ser) variant of TSLP (Thymic stromal lymphopoietin)
Y8S (p.Tyr8Ser) in TSLP (Thymic stromal lymphopoietin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
Y8S (p.Tyr8Ser) variant details
- p.Tyr8Ser
- gnomAD 5-111071913-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- REVEL 0.11
- CADD 5.16
- PolyPhen-2 0.00
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available