Y8C (p.Tyr8Cys) variant of TSLP (Thymic stromal lymphopoietin)
Y8C (p.Tyr8Cys) in TSLP (Thymic stromal lymphopoietin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
Y8C (p.Tyr8Cys) variant details
- p.Tyr8Cys
- 1000Genomes rs564641413
- ExAC rs564641413
- TOPMed rs564641413
- gnomAD rs564641413
- Missense
- Variant Prioritization Score for Impact Estimate 0.189
- REVEL 0.04
- CADD 10.80
- PolyPhen-2 0.00
- SIFT 0.01
- Most common in the 1KG:GWD population (allele frequency 0.0043)
- Structural context available