Y29D (p.Tyr29Asp) variant of TSLP (Thymic stromal lymphopoietin)
Y29D (p.Tyr29Asp) in TSLP (Thymic stromal lymphopoietin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
Y29D (p.Tyr29Asp) variant details
- p.Tyr29Asp
- gnomAD 5-111071975-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.448
- REVEL 0.46
- CADD 24.80
- PolyPhen-2 0.97
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available