S60I (p.Ser60Ile) variant of TSLP (Thymic stromal lymphopoietin)
S60I (p.Ser60Ile) in TSLP (Thymic stromal lymphopoietin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
S60I (p.Ser60Ile) variant details
- p.Ser60Ile
- TOPMed rs889977306
- gnomAD rs889977306
- Missense
- Variant Prioritization Score for Impact Estimate 0.316
- REVEL 0.07
- CADD 21.20
- PolyPhen-2 0.68
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available