S11L (p.Ser11Leu) variant of TSLP (Thymic stromal lymphopoietin)
S11L (p.Ser11Leu) in TSLP (Thymic stromal lymphopoietin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
S11L (p.Ser11Leu) variant details
- p.Ser11Leu
- 1000Genomes rs200322626
- ExAC rs200322626
- TOPMed rs200322626
- gnomAD rs200322626
- Missense
- Variant Prioritization Score for Impact Estimate 0.409
- REVEL 0.27
- CADD 24.40
- PolyPhen-2 0.92
- SIFT 0.02
- Most common in the 1KG:CEU population (allele frequency 0.0042)
- Structural context available