L7V (p.Leu7Val) variant of TSLP (Thymic stromal lymphopoietin)
L7V (p.Leu7Val) in TSLP (Thymic stromal lymphopoietin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
L7V (p.Leu7Val) variant details
- p.Leu7Val
- gnomAD 5-111071909-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.381
- REVEL 0.12
- CADD 19.10
- PolyPhen-2 0.98
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available