L7I (p.Leu7Ile) variant of TSLP (Thymic stromal lymphopoietin)
L7I (p.Leu7Ile) in TSLP (Thymic stromal lymphopoietin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
L7I (p.Leu7Ile) variant details
- p.Leu7Ile
- gnomAD rs1257910285
- Missense
- Variant Prioritization Score for Impact Estimate 0.363
- REVEL 0.10
- CADD 16.40
- PolyPhen-2 0.98
- SIFT 0.02
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available