L6F (p.Leu6Phe) variant of TSLP (Thymic stromal lymphopoietin)
L6F (p.Leu6Phe) in TSLP (Thymic stromal lymphopoietin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
L6F (p.Leu6Phe) variant details
- p.Leu6Phe
- gnomAD 5-111071908-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.142
- REVEL 0.09
- CADD 18.90
- PolyPhen-2 0.94
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)
- Structural context available
- Literature evidence available