L51P (p.Leu51Pro) variant of TSLP (Thymic stromal lymphopoietin)
L51P (p.Leu51Pro) in TSLP (Thymic stromal lymphopoietin) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
L51P (p.Leu51Pro) variant details
- p.Leu51Pro
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.466
- REVEL 0.35
- CADD 23.60
- PolyPhen-2 1.00
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available