L25Q (p.Leu25Gln) variant of TSLP (Thymic stromal lymphopoietin)
L25Q (p.Leu25Gln) in TSLP (Thymic stromal lymphopoietin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
L25Q (p.Leu25Gln) variant details
- p.Leu25Gln
- gnomAD 5-111071964-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.393
- REVEL 0.32
- CADD 25.90
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available