L22V (p.Leu22Val) variant of TSLP (Thymic stromal lymphopoietin)
L22V (p.Leu22Val) in TSLP (Thymic stromal lymphopoietin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
L22V (p.Leu22Val) variant details
- p.Leu22Val
- ExAC rs768686022
- TOPMed rs768686022
- gnomAD rs768686022
- Missense
- Variant Prioritization Score for Impact Estimate 0.106
- REVEL 0.05
- CADD 8.59
- PolyPhen-2 0.39
- SIFT 0.13
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available