L22F (p.Leu22Phe) variant of TSLP (Thymic stromal lymphopoietin)
L22F (p.Leu22Phe) in TSLP (Thymic stromal lymphopoietin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
L22F (p.Leu22Phe) variant details
- p.Leu22Phe
- ExAC rs768686022
- TOPMed rs768686022
- gnomAD rs768686022
- Missense
- Variant Prioritization Score for Impact Estimate 0.254
- REVEL 0.23
- CADD 20.80
- PolyPhen-2 0.96
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available