L20I (p.Leu20Ile) variant of TSLP (Thymic stromal lymphopoietin)
L20I (p.Leu20Ile) in TSLP (Thymic stromal lymphopoietin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
L20I (p.Leu20Ile) variant details
- p.Leu20Ile
- TOPMed rs759901388
- gnomAD rs759901388
- Missense
- Variant Prioritization Score for Impact Estimate 0.374
- REVEL 0.27
- CADD 23.20
- PolyPhen-2 0.67
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.3e-05)
- Structural context available