L10P (p.Leu10Pro) variant of TSLP (Thymic stromal lymphopoietin)
L10P (p.Leu10Pro) in TSLP (Thymic stromal lymphopoietin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
L10P (p.Leu10Pro) variant details
- p.Leu10Pro
- gnomAD rs1431494215
- Missense
- Variant Prioritization Score for Impact Estimate 0.327
- REVEL 0.30
- CADD 22.90
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available