K16I (p.Lys16Ile) variant of TSLP (Thymic stromal lymphopoietin)
K16I (p.Lys16Ile) in TSLP (Thymic stromal lymphopoietin) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
K16I (p.Lys16Ile) variant details
- p.Lys16Ile
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.204
- REVEL 0.12
- CADD 22.90
- PolyPhen-2 0.28
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available