I47L (p.Ile47Leu) variant of TSLP (Thymic stromal lymphopoietin)
I47L (p.Ile47Leu) in TSLP (Thymic stromal lymphopoietin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
I47L (p.Ile47Leu) variant details
- p.Ile47Leu
- gnomAD 5-111072029-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.228
- REVEL 0.15
- CADD 23.00
- PolyPhen-2 0.99
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available