I39T (p.Ile39Thr) variant of TSLP (Thymic stromal lymphopoietin)
I39T (p.Ile39Thr) in TSLP (Thymic stromal lymphopoietin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
I39T (p.Ile39Thr) variant details
- p.Ile39Thr
- gnomAD 5-111072006-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.418
- REVEL 0.27
- CADD 23.00
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available