I39L (p.Ile39Leu) variant of TSLP (Thymic stromal lymphopoietin)
I39L (p.Ile39Leu) in TSLP (Thymic stromal lymphopoietin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
I39L (p.Ile39Leu) variant details
- p.Ile39Leu
- ExAC rs758300677
- gnomAD rs758300677
- Missense
- Variant Prioritization Score for Impact Estimate 0.324
- REVEL 0.27
- CADD 15.80
- PolyPhen-2 0.73
- SIFT 0.06
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available