I19M (p.Ile19Met) variant of TSLP (Thymic stromal lymphopoietin)
I19M (p.Ile19Met) in TSLP (Thymic stromal lymphopoietin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
I19M (p.Ile19Met) variant details
- p.Ile19Met
- gnomAD 5-111071947-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.219
- REVEL 0.14
- CADD 21.90
- PolyPhen-2 0.89
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available