I17T (p.Ile17Thr) variant of TSLP (Thymic stromal lymphopoietin)
I17T (p.Ile17Thr) in TSLP (Thymic stromal lymphopoietin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
I17T (p.Ile17Thr) variant details
- p.Ile17Thr
- gnomAD 5-111071940-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.383
- REVEL 0.21
- CADD 24.60
- PolyPhen-2 0.49
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available