F4L (p.Phe4Leu) variant of TSLP (Thymic stromal lymphopoietin)
F4L (p.Phe4Leu) in TSLP (Thymic stromal lymphopoietin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
F4L (p.Phe4Leu) variant details
- p.Phe4Leu
- gnomAD 5-111071902-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.218
- REVEL 0.01
- CADD 10.40
- PolyPhen-2 0.01
- SIFT 0.13
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available
- Literature evidence available