D35Y (p.Asp35Tyr) variant of TSLP (Thymic stromal lymphopoietin)
D35Y (p.Asp35Tyr) in TSLP (Thymic stromal lymphopoietin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
D35Y (p.Asp35Tyr) variant details
- p.Asp35Tyr
- gnomAD 5-111071993-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.223
- REVEL 0.21
- CADD 22.60
- PolyPhen-2 0.87
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available