D35N (p.Asp35Asn) variant of TSLP (Thymic stromal lymphopoietin)
D35N (p.Asp35Asn) in TSLP (Thymic stromal lymphopoietin) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of not specified. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
D35N (p.Asp35Asn) variant details
- p.Asp35Asn
- rs753501114
- ClinGen CA3364882
- ClinVar RCV004309145
- ExAC rs753501114
- Uncertain significance
- not specified
- Missense
- Variant Prioritization Score for Impact Estimate 0.0958
- REVEL 0.04
- CADD 14.40
- PolyPhen-2 0.01
- SIFT 0.24
- ClinVar: Uncertain significance (not specified)
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Most common in the East Asian population (allele frequency 0.00013)
- Structural context available