D30N (p.Asp30Asn) variant of TSLP (Thymic stromal lymphopoietin)
D30N (p.Asp30Asn) in TSLP (Thymic stromal lymphopoietin) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
D30N (p.Asp30Asn) variant details
- p.Asp30Asn
- rs765465942
- NCI-TCGA Cosmic COSV1007
- NCI-TCGA Cosmic COSV6129
- cosmic curated COSV61291
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.167
- REVEL 0.04
- CADD 13.10
- PolyPhen-2 0.00
- SIFT 1.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available