S36T (p.Ser36Thr) variant of TPM1 (Tropomyosin alpha-1 chain)
S36T (p.Ser36Thr) in TPM1 (Tropomyosin alpha-1 chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
S36T (p.Ser36Thr) variant details
- p.Ser36Thr
- gnomAD 15-63042936-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.507
- REVEL 0.36
- CADD 23.20
- PolyPhen-2 0.00
- SIFT 0.24
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available