R21R (p.Arg21Arg) variant of TPM1 (Tropomyosin alpha-1 chain)
R21R (p.Arg21Arg) in TPM1 (Tropomyosin alpha-1 chain) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
R21R (p.Arg21Arg) variant details
- p.Arg21Arg
- rs1437698471
- gnomAD 15-63042890-C-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.475
- CADD 16.90
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available