K59T (p.Lys59Thr) variant of TPM1 (Tropomyosin alpha-1 chain)
K59T (p.Lys59Thr) in TPM1 (Tropomyosin alpha-1 chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
K59T (p.Lys59Thr) variant details
- p.Lys59Thr
- TOPMed rs2031861291
- Missense
- Variant Prioritization Score for Impact Estimate 0.514
- REVEL 0.46
- CADD 23.90
- PolyPhen-2 0.01
- SIFT 0.17
- Population evidence available
- Structural context available