K37N (p.Lys37Asn) variant of TPM1 (Tropomyosin alpha-1 chain)
K37N (p.Lys37Asn) in TPM1 (Tropomyosin alpha-1 chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
K37N (p.Lys37Asn) variant details
- p.Lys37Asn
- gnomAD 15-63042940-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.347
- REVEL 0.37
- CADD 22.50
- PolyPhen-2 0.14
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available