K29R (p.Lys29Arg) variant of TPM1 (Tropomyosin alpha-1 chain)
K29R (p.Lys29Arg) in TPM1 (Tropomyosin alpha-1 chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
K29R (p.Lys29Arg) variant details
- p.Lys29Arg
- Ensembl rs2140596080
- Missense
- Variant Prioritization Score for Impact Estimate 0.454
- REVEL 0.36
- CADD 23.30
- PolyPhen-2 0.00
- SIFT 0.15
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available