W23* (p.Trp23Ter) variant of TP53 (Cellular tumor antigen p53)
W23* (p.Trp23Ter) in TP53 (Cellular tumor antigen p53) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The record also includes experimental measurements and structural context.
W23* (p.Trp23Ter) variant details
- p.Trp23Ter
- cosmic curated COSV53381
- Ensembl rs2151047253
- NCI-TCGA Cosmic COSV5293
- cosmic curated COSV52932
- Variant assessed as somatic; high impact.
- Stop Gained
- UniProt: Variant assessed as somatic; high impact.
- Structural context available
- p53 variant effect measured by cell growth: score -2.64