T18A (p.Thr18Ala) variant of TP53 (Cellular tumor antigen p53)
T18A (p.Thr18Ala) in TP53 (Cellular tumor antigen p53) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes experimental measurements and structural context.
T18A (p.Thr18Ala) variant details
- p.Thr18Ala
- cosmic curated COSV53626
- Missense
- Variant Prioritization Score for Impact Estimate 0.228
- ESM-1b 0.00
- AlphaMissense 0.49
- Structural context available
- p53 variant effect measured by cell growth: score -1.65