S15T (p.Ser15Thr) variant of TP53 (Cellular tumor antigen p53)
S15T (p.Ser15Thr) in TP53 (Cellular tumor antigen p53) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes experimental measurements and structural context.
S15T (p.Ser15Thr) variant details
- p.Ser15Thr
- TOPMed rs2073520420
- gnomAD rs2073520420
- Missense
- Variant Prioritization Score for Impact Estimate 0.676
- REVEL 0.75
- ESM-1b 0.00
- AlphaMissense 0.34
- MetaLR 0.98
- MetaSVM 1.04
- SIFT 0.04
- Structural context available
- p53 variant effect measured by cell growth: score -2.99