S15K (p.Ser15Lys) variant of TP53 (Cellular tumor antigen p53)
S15K (p.Ser15Lys) in TP53 (Cellular tumor antigen p53) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact in the context of in a sporadic cancer. The record also includes experimental measurements and structural context.
S15K (p.Ser15Lys) variant details
- p.Ser15Lys
- NCI-TCGA TCGA novel
- Variant assessed as somatic; high impact.
- in a sporadic cancer
- Frameshift
- UniProt: Variant assessed as somatic; high impact. (in a sporadic cancer)
- Structural context available
- p53 variant effect measured by cell growth: score -2.99