L22R (p.Leu22Arg) variant of TP53 (Cellular tumor antigen p53)
L22R (p.Leu22Arg) in TP53 (Cellular tumor antigen p53) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.93 / 1. The record also includes experimental measurements and structural context.
L22R (p.Leu22Arg) variant details
- p.Leu22Arg
- Ensembl rs2151047296
- Missense
- Variant Prioritization Score for Impact Estimate 0.929
- ESM-1b 1.00
- AlphaMissense 0.84
- Structural context available
- p53 variant effect measured by cell growth: score -2.39