L22Q (p.Leu22Gln) variant of TP53 (Cellular tumor antigen p53)
L22Q (p.Leu22Gln) in TP53 (Cellular tumor antigen p53) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.94 / 1. The record also includes experimental measurements and structural context.
L22Q (p.Leu22Gln) variant details
- p.Leu22Gln
- Ensembl rs2151047296
- Missense
- Variant Prioritization Score for Impact Estimate 0.944
- ESM-1b 1.00
- AlphaMissense 0.88
- Structural context available
- p53 variant effect measured by cell growth: score -2.39