L22P (p.Leu22Pro) variant of TP53 (Cellular tumor antigen p53)
L22P (p.Leu22Pro) in TP53 (Cellular tumor antigen p53) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes experimental measurements and structural context.
L22P (p.Leu22Pro) variant details
- p.Leu22Pro
- Ensembl rs2151047296
- Missense
- Variant Prioritization Score for Impact Estimate 0.358
- ESM-1b 0.21
- AlphaMissense 0.96
- Structural context available
- p53 variant effect measured by cell growth: score -2.39