L22I (p.Leu22Ile) variant of TP53 (Cellular tumor antigen p53)
L22I (p.Leu22Ile) in TP53 (Cellular tumor antigen p53) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes experimental measurements and structural context.
L22I (p.Leu22Ile) variant details
- p.Leu22Ile
- Ensembl rs2151047310
- Missense
- Variant Prioritization Score for Impact Estimate 0.262
- ESM-1b 0.00
- AlphaMissense 0.16
- Structural context available
- p53 variant effect measured by cell growth: score -2.39