F19Y (p.Phe19Tyr) variant of TP53 (Cellular tumor antigen p53)
F19Y (p.Phe19Tyr) in TP53 (Cellular tumor antigen p53) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes experimental measurements and structural context.
F19Y (p.Phe19Tyr) variant details
- p.Phe19Tyr
- Ensembl rs2151047443
- Missense
- Variant Prioritization Score for Impact Estimate 0.733
- REVEL 0.83
- ESM-1b 0.00
- AlphaMissense 0.69
- MetaLR 0.99
- MetaSVM 1.02
- SIFT 0.12
- Structural context available
- p53 variant effect measured by cell growth: score -2.47