E17V (p.Glu17Val) variant of TP53 (Cellular tumor antigen p53)
E17V (p.Glu17Val) in TP53 (Cellular tumor antigen p53) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes experimental measurements and structural context.
E17V (p.Glu17Val) variant details
- p.Glu17Val
- Ensembl rs2151047516
- Missense
- Variant Prioritization Score for Impact Estimate 0.652
- REVEL 0.70
- ESM-1b 0.00
- AlphaMissense 0.56
- MetaLR 0.98
- MetaSVM 1.07
- SIFT 0.12
- Structural context available
- p53 variant effect measured by cell growth: score -2.25