D21V (p.Asp21Val) variant of TP53 (Cellular tumor antigen p53)
D21V (p.Asp21Val) in TP53 (Cellular tumor antigen p53) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.82 / 1. The record also includes experimental measurements and structural context.
D21V (p.Asp21Val) variant details
- p.Asp21Val
- Ensembl rs2151047348
- Missense
- Variant Prioritization Score for Impact Estimate 0.824
- REVEL 0.84
- ESM-1b 1.00
- AlphaMissense 0.18
- MetaLR 0.97
- MetaSVM 1.10
- SIFT 0.31
- Structural context available
- p53 variant effect measured by cell growth: score -3.41