W9L (p.Trp9Leu) variant of TIGIT (Q495A1)
W9L (p.Trp9Leu) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
W9L (p.Trp9Leu) variant details
- p.Trp9Leu
- gnomAD 3-114294087-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.513
- REVEL 0.44
- MetaLR 0.38
- MetaSVM -0.13
- CADD 27.20
- PolyPhen-2 1.00
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available