W9G (p.Trp9Gly) variant of TIGIT (Q495A1)
W9G (p.Trp9Gly) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, published literature, and structural context.
W9G (p.Trp9Gly) variant details
- p.Trp9Gly
- gnomAD 3-114294086-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.559
- REVEL 0.61
- MetaLR 0.37
- MetaSVM -0.12
- CADD 29.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available
- Literature evidence available